Vol. 6 No. 1 (2023): The Reality of Women in Science

• G J Clarkson
  Chemistry Department, University of Warwick. U.K.
  




• C A Adah
  Chemistry Department, Benue State University, Makurdi
  

The reactions of galactosyl, mannosyl and lactosyl barbiturates with 4-benzyloxybenzyl chloride and á- halo amide with galactose barbiturate were investigated. The products (benzyloxybenzyl-galactosyl barbiturate, benzyloxybenzyl-mannosyl barbiturate, benzyloxybenzyl-lactosyl barbiturate and galactose amide) were characterised by high field nuclear magnetic resonance spectroscopy, mass spectrometry, carbon, hydrogen and nitrogen combustion analyses and further characterised as per- acetate. The alkylation or the barbituric salts proceeds well with the electrophiles and are routes to novel C-glycosyl lectin binders.

Keywords: Alkylation, galactosyl, mannosyl, actosyl barbiturates